Slice the beef brisket into large chunks and season with salt and pepper. Next, heat the olive oil in a large pan and sear all the sides on the beef. Once all the sides are seared add the meat into the slow cooker.
Combine all of the remaining ingredients into a large blender or food processor and blend on low until smooth.
Pour the finished sauce over the seared beef in the crockpot. Cook on LOW for 8-9 hours or HIGH for 6 hours. Once the meat is extremely tender and falling apart you know it is finished.
Once the meat is cooked shred it and add to your recipe of choice or eat alone with rice and beans. Additionally, you can add more lime juice or fresh cilantro over top to enhance the flavor. Enjoy!